Serum iron markers are inadequate for guiding iron repletion in chronic kidney disease
P Ferrari, H Kulkarni, S Dheda
Clin J Am Soc Nephrol 2010
This US based study examined the relationship between parenteral iron therapy, conventional serum iron markers and liver iron concentration (LIC) using magnetic resonance R2 relaxometry in 25 ID predialysis CKD patients before, and 2 and 12 weeks after single high-dose i.v. iron and in 15 chronic haemodialysis (HD) patients with elevated serum ferritin (>500 μg/L).
The results suggest that in haemodialysis patients transferrin saturation and ferritin are poor indicators of body iron load.
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