What causes anaemia in patients with cardiorenal syndrome?
The origin of anaemia in cardiorenal syndrome is multifactorial.1
- Renal insufficiency can directly cause anaemia through reduced erythropoietin production.
- Causes of anaemia in CHF includes inflammation, reduced erythropoietin (EPO) production and EPO resistance, iron deficiency, diabetes, haemodilution, and gastrointestinal blood loss.2
1.Silverberg DS et al. Clin Nephrol 2002;58 Suppl 1:S37–45
2. Jankowska E and Ponikowski P. Heart Failure Clin 6 (2010) 295–304